Does the relative silicone content of different syringes affect the stability of foam in sclerotherapy?

Lai SW, Goldman MP.
Dermatology/Cosmetic Laser Associates of La Jolla Inc, La Jolla, CA 92037, USA.

BACKGROUND: Sclerotherapy has become the gold standard in the treatment of varicose veins. Foam sclerosing solution with sodium tetradecyl sulfate (STS) is one of the most popular agents used. This study examined the possibility that relative silicone content of different syringes may affect the overall foam stability.

MATERIALS AND METHODS: A double-syringe system (DSS) technique to make sclerosing foam (STS 0.5% and air) was applied. Four different brands of syringes were tested. The time required for half of the original volume of sclerosing solution to settle was recorded.

RESULTS: The time for the sclerosing solution to settle to half of its initial volume varied with each brand of syringes.

CONCLUSION: The type of syringe used in the DSS technique to produce foam for sclerotherapy is a determinant of foam stability. Whether this will affect the result of sclerotherapy requires further investigation.

J Drugs Dermatol. 2008 Apr;7(4):399-400.